Molecular Genetic & Biochemical
Mycobacterium immunogenum in metalworking fluids [MIPCR]
Exposure to semisynthetic and synthetic metalworking fluids (MWF) has been associated with work-related asthma, hypersensitivity pneumonitis and dermatitis. Exposure to microbial contaminants in MWFs appears to be a key factor in the etiology of these diseases in machinists. Recently released occupational exposure limits to MWFs are based on aerosol concentrations determined by gravimetric measurements that […]
Endotoxin [ENDO]
Endotoxin is a lipopolysaccharide found in the cell membranes of Gram-negative bacteria. Endotoxin is a strongly proinflammatory material because of its interactions with receptors that stimulate the innate immune system. Exposure to endotoxin will initiate a strong inflammatory response in anyone and does not require allergic sensitization or individual sensitivity. Inhalation exposure to endotoxin is […]
Bacterial DNA barcode sequence identification [BDNA]
This test provides a low-level identification of a single bacterial isolate by sequencing of portions of the 16S ribosomal small subunit gene region. DNA-based sequence identification is the gold-standard for microbial identification, since it is capable of identifying rare or atypical isolates of bacteria irrespective of their responses to diagnostic culture media or biochemical tests. […]